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Mebendazole is an antiparasitic medication widely used in humans to treat infections caused by intestinal worms. It belongs to the benzimidazole class of drugs and works by interfering with the parasites’ ability to absorb glucose, which eventually leads to their death. Mebendazole 100 mg is commonly prescribed for infections such as roundworm, hookworm, whipworm , pinworm, and certain mixed worm infestations. By targeting the metabolic processes of the worms rather than the human host, the drug is generally well tolerated. In humans, mebendazole is valued for its effectiveness, ease of administration, and relatively low risk of serious side effects. It is usually taken orally and acts primarily within the gastrointestinal tract, with minimal absorption into the bloodstream. This localized action helps reduce systemic adverse effects. Common side effects, when they occur, are typically mild and may include abdominal pain, diarrhea, nausea, or headache, often related to the body’s response to dying parasites. Mebendazole plays an important role in public health, especially in regions where soil-transmitted helminth infections are common. It is frequently used in deworming programs to improve nutrition, growth, and overall health, particularly in children. When used appropriately under medical guidance, mebendazole is a safe and effective treatment for human parasitic worm infections.